Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.47 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082813 | 0.83 | GFER (0.57) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL11079223 | 0.83 | KDM4E (0.72) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL11155548 | 0.81 | L3MBTL1 (0.61) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL11076159 | 0.78 | ADRB2 (0.57) | KMT2APOLBMEN1KCNH2ALDH1A1 | |
| SCHEMBL3332171 | 0.78 | HRH3 (0.58) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL21423847 | 0.76 | PANK3 (0.68) | KMT2APOLBMEN1RECQLALDH1A1 | |
| SCHEMBL1876940 | 0.76 | RECQL (0.72) | KMT2APOLBMEN1RECQLKCNJ1 | |
| SCHEMBL12611028 | 0.76 | KMT2A (0.90) | KMT2APOLBMEN1RECQLKCNJ1 | |
| SCHEMBL11077598 | 0.75 | ATM (0.51) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11071969 | 0.75 | POLB (0.60) | KMT2APOLBRECQLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |