Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082813 | 0.87 | GFER (0.57) | KMT2APANK3KDM4EALDH1A1HPGD | |
| SCHEMBL11077598 | 0.85 | ATM (0.51) | KMT2APANK3KDM4EALDH1A1HPGD | |
| SCHEMBL11079223 | 0.82 | KDM4E (0.72) | KMT2APANK3KDM4EALDH1A1HPGD | |
| SCHEMBL11079083 | 0.81 | KDM4E (0.57) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11071969 | 0.81 | POLB (0.60) | KMT2APANK3KDM4EALDH1A1HPGD | |
| SCHEMBL11077464 | 0.78 | KMT2A (0.58) | KCNH2KMT2APANK3KDM4EALDH1A1 | |
| SCHEMBL22481434 | 0.77 | SLC6A7 (0.53) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3332171 | 0.76 | HRH3 (0.58) | KMT2APANK3KDM4EALDH1A1HPGD | |
| SCHEMBL14411664 | 0.76 | SLC6A7 (0.54) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14224744 | 0.74 | CKS1B (0.53) | KMT2AKDM4EALDH1A1SLC6A7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0094498-A2 | Antiatherosclerotic 1-piperazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1983-11-23 | — | — | EP | disclosed |