Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.51 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287852 | 0.83 | ALDH1A1 (0.54) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL11287622 | 0.83 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL11287621 | 0.83 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL11073174 | 0.83 | LMNA (0.51) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL23982402 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL8205660 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL4425824 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL11423681 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL13597931 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 | |
| SCHEMBL10033986 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1TP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352795-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-10-05 | — | — | US | claimed |
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | claimed |
| US-4439604-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| US-4352795-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |