Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.63 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.63 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.63 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.63 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.63 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.63 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.56 |
| ▸ | AHCY | P23526 | 2/20 | 0.54 |
| ▸ | MARS1 | P56192 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425824 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL31685764 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL19889158 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL11423681 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL13597931 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL23982402 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL10033986 | 1.00 | ALDH1A1 (0.65) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL6744875 | 0.92 | AHCY (0.59) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL10587115 | 0.92 | AHCY (0.59) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL9300768 | 0.91 | PRKAB2 (0.56) | ALDH1A1LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324708-A1 | COMPOUND HAVING INHIBITORY ACTIVITY ON A RHO-GTPASE CELL PROTEIN, A PROCESS FOR OBTAINING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF AND A METHOD FOR THE TREATMENT OF RHO-GTPASE CELL PROTEIN-MEDIATED CONDITION | UNIVERSIDAD NACIONAL DE QUILMES (AR) | 2009-12-31 | — | — | US | disclosed |
| WO-2008055875-A1 | COMPOUND HAVING INHIBITORY ACTIVITY ON A RHO-GTPASE CELL PROTEIN, A PROCESS FOR OBTAINING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISION THEREOF AND A METHOD FOR THE TREATMENT OF A RHO-GTPASE CELL PROTEIN-MEDIATED CONDITION | UNIVERSIDAD NACIONAL DE QUILMES (AR) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324708-A1 | COMPOUND HAVING INHIBITORY ACTIVITY ON A RHO-GTPASE CELL PROTEIN, A PROCESS FOR OBTAINING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF AND A METHOD FOR THE TREATMENT OF RHO-GTPASE CELL PROTEIN-MEDIATED CONDITION | RHOA, ARHGDIA, ARHGDIB | ALDH1A1 4493/4885LMNA 4307/4885TP53 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.