Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901097 | 0.73 | ALDH1A1 (0.37) | SELEVCAM1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL6967658 | 0.71 | USP2 (0.47) | SELEVCAM1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL22789253 | 0.71 | GAA (0.38) | SELEVCAM1ALDH1A1MAPK1CYP1A2 | |
| Hydrochloric Acid SCHEMBL22775101 | 0.70 | GAA (0.37) | SELEVCAM1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL29093281 | 0.68 | MAPK1 (0.32) | SELEVCAM1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL3790404 | 0.68 | ALDH1A1 (0.34) | SELEVCAM1ALDH1A1MAPK1GAA | |
| SCHEMBL22789209 | 0.68 | MAPK1 (0.32) | SELEVCAM1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL29093468 | 0.67 | MAPK1 (0.31) | SELEVCAM1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL6967703 | 0.67 | ALDH1A1 (0.58) | SELEVCAM1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL9631989 | 0.67 | SELE (0.33) | SELEVCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002846-B1 | 3-THIENYLMALONIC ACIDS, THE CORRESPONDING DIESTERS AND THEIR PREPARATION | Océ-Andeno B.V. (NL) | 1984-05-23 | — | — | EP | disclosed |
| EP-0002304-B1 | METHOD OF PREPARING A 3-IODOTHIOPHENE | Océ-Andeno B.V. (NL) | 1982-09-29 | — | — | EP | disclosed |
| US-4262129-A | Preparation of a 3-thienylmalonic acid and the corresponding diesters | OCE-ANDENO B.V. (NL) | 1981-04-14 | — | — | US | disclosed |
| US-4169839-A | REACTING 3-BROMOTHIOPHENE COMPOUND WITH COPPER IODIDE IN APROTIC SOLVENT | OCE-ANDENO B.V. (NL) | 1979-10-02 | — | — | US | disclosed |
| EP-0002846-A1 | 3-Thienylmalonic acids, the corresponding diesters and their preparation | Océ-Andeno B.V. (NL) | 1979-07-11 | — | — | EP | disclosed |