Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468694 | 0.98 | KDM4E (0.60) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL9008311 | 0.92 | ROCK2 (0.58) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL29447185 | 0.92 | ROCK2 (0.58) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL20339234 | 0.84 | ROCK2 (0.51) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL30638321 | 0.84 | FLT3 (0.52) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL25042152 | 0.84 | ROCK2 (0.51) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL29448240 | 0.84 | ROCK2 (0.51) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL17710614 | 0.84 | FLT3 (0.52) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL7324752 | 0.84 | HTR6 (0.55) | KDM4EALDH1A1KMT2AEPHX1MEN1 | |
| SCHEMBL30279069 | 0.84 | ROCK2 (0.51) | KDM4EALDH1A1KMT2AEPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452943-A | ADDING NITRILE-CONTAINING MATERIAL TO NON-POLAR THERMOPLASTIC POLYMER | GOLDMAN CONRAD | 1984-06-05 | — | — | US | disclosed |