Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7324023 | 0.98 | HTR6 (0.56) | HTR6BRD4ATAD2NSD2IRAK4 | |
| Hydrochloric Acid SCHEMBL5179688 | 0.98 | HTR6 (0.56) | HTR6BRD4ATAD2NSD2IRAK4 | |
| SCHEMBL21460267 | 0.90 | PRKCZ (0.59) | HTR6BRD4ATAD2NSD2PRKCZ | |
| SCHEMBL9008311 | 0.87 | ROCK2 (0.58) | NSD2ROCK2ROCK1KDM4ESMN1; SMN2 | |
| SCHEMBL29447185 | 0.87 | ROCK2 (0.58) | NSD2ROCK2ROCK1KDM4ESMN1; SMN2 | |
| SCHEMBL11077693 | 0.84 | KDM4E (0.58) | NSD2PRKCZROCK2ROCK1KDM4E | |
| SCHEMBL2468694 | 0.82 | KDM4E (0.60) | NSD2PRKCZROCK2ROCK1KDM4E | |
| SCHEMBL5664354 | 0.82 | ROCK2 (0.74) | IRAK4PRKCZROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL23360436 | 0.81 | ROCK2 (0.57) | HTR6BRD4ATAD2NSD2IRAK4 | |
| Hydrochloric Acid SCHEMBL5662581 | 0.81 | ROCK2 (0.72) | IRAK4PRKCZROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006828-A1 | PIPERIDINOALKYL ARYL ETHERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1996-03-07 | — | — | WO | claimed |
| WO-1996006828-A1 | PIPERIDINOALKYL ARYL ETHERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1996-03-07 | — | — | WO | disclosed |
| CN-1080918-A | Novel aminopropanol derivatives, pharmaceutical compositions containing them and process for preparing them | RICHTER GEDEON VEGYESZET (HU) | 1994-01-19 | — | — | CN | disclosed |
| WO-1993025528-A1 | NOVEL AMINOPROPANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1993-12-23 | — | — | WO | disclosed |