Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071467 | 0.75 | SKP2 (0.38) | OPRL1OPRM1 | |
| Ethylbenzene SCHEMBL11069651 | 0.74 | OPRL1 (0.47) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11078781 | 0.72 | OPRL1 (0.43) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11077902 | 0.72 | SLC6A4 (0.39) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11071916 | 0.70 | OPRM1 (0.38) | OPRL1OPRM1L3MBTL1IRAK4 | |
| SCHEMBL11070312 | 0.70 | OPRM1 (0.44) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11070140 | 0.70 | OPRL1 (0.55) | OPRL1OPRM1L3MBTL1 | |
| SCHEMBL11073735 | 0.69 | OPRL1 (0.38) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11070178 | 0.69 | OPRL1 (0.51) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11096498 | 0.68 | MEN1 (0.40) | OPRL1OPRM1GAAHDAC4OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |