Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332981 | 0.88 | HSD17B10 (0.63) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL30436820 | 0.87 | HSD17B10 (0.71) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL266527 | 0.87 | NPC1 (0.58) | MTNR1AMTNR1BHSD17B10KDM4ENPC1 | |
| SCHEMBL491188 | 0.87 | HSD17B10 (0.71) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL64208 | 0.85 | MTNR1A (0.61) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL7196334 | 0.84 | HSD17B10 (0.58) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL2090274 | 0.83 | NPC1 (0.58) | KDM4ENPC1LMNATP53CYP1A2 | |
| SCHEMBL5743959 | 0.83 | HSD17B10 (0.75) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL7060135 | 0.83 | MTNR1A (0.58) | MTNR1AMTNR1BHSD17B10ADRA1ATAAR1 | |
| SCHEMBL26046405 | 0.82 | LMNA (0.56) | MTNR1AMTNR1BHSD17B10KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452801-A | ANTIINFLAMMATORY AGENTS, ANTICOAGULATNS, ANTIALLERGENS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4360532-A | ANTIINFLAMMATORY AGENTS, ANTICOAGULANTS, ANTIALLERGENS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4321270-A | ANTIINFLAMMATORY AGENT, ANTIAGGLOMERANTS, AND HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-03-23 | — | — | US | disclosed |