Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992686 | 0.88 | KDM4E (0.46) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL7051565 | 0.88 | KDM4E (0.68) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9320904 | 0.86 | KDM4E (0.56) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9570278 | 0.82 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9319225 | 0.82 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL28433722 | 0.81 | KDM4E (0.62) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL13596328 | 0.81 | KDM4E (0.62) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9318828 | 0.80 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL28331869 | 0.80 | DRD3 (0.59) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL501895 | 0.79 | DRD3 (0.68) | KDM4EHPGDHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468394-A | Cephalosporin compounds | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| EP-0062328-A2 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds | Eisai Co., Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |