Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13596328 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL28433722 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL11078022 | 0.88 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL7057820 | 0.85 | LMNA (0.65) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL9320904 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL9570278 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL15992147 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL11815418 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL5459961 | 0.81 | MAPT (0.66) | MAPTTP53LMNAPOLBGAA | |
| SCHEMBL7282582 | 0.81 | LMNA (0.60) | KDM4EALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841929-B1 | QUINOLONES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-5891878-A | Quinolones and their therapeutic use | CHIROSCIENCE LIMITED (GB) | 1999-04-06 | — | — | US | disclosed |
| US-3963736-A | Preparation of 1-(lower alkyl)-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-06-15 | — | — | US | disclosed |