Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078022 | 0.86 | KDM4E (0.60) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL7051565 | 0.84 | KDM4E (0.68) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9570278 | 0.79 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9319225 | 0.79 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL28433722 | 0.78 | KDM4E (0.62) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL13596328 | 0.78 | KDM4E (0.62) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL28434308 | 0.77 | KDM4E (0.53) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9318828 | 0.77 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL28331869 | 0.77 | DRD3 (0.59) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL501895 | 0.76 | DRD3 (0.68) | KDM4EHPGDHSD17B10ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |