Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080932 | 0.90 | SLC6A7 (0.85) | SLC6A7ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9763711 | 0.85 | PKM (0.74) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| Hydrochloric Acid SCHEMBL1596692 | 0.83 | PKM (0.72) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL13149233 | 0.83 | KDM4E (0.71) | SLC6A7ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3575539 | 0.83 | SLC6A7 (1.00) | SLC6A7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL94351 | 0.82 | SLC6A7 (0.73) | SLC6A7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19562177 | 0.82 | SLC6A7 (0.73) | SLC6A7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12082792 | 0.82 | SLC6A7 (0.73) | SLC6A7KDM4ESMN1; SMN2MEN1MAPT | |
| SCHEMBL27872912 | 0.82 | SLC6A7 (0.69) | SLC6A7ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1108658 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4ESMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |