Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | SLC6A7 | Q99884 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763711 | 0.87 | PKM (0.74) | KDM4EMEN1MAPTKMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1596692 | 0.86 | PKM (0.72) | KDM4EMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL12933024 | 0.86 | MAPT (0.56) | KDM4ESLC6A7MEN1MAPTKMT2A | |
| SCHEMBL30165123 | 0.86 | SLC6A7 (0.60) | KDM4ESLC6A7MEN1MAPTKMT2A | |
| SCHEMBL3585560 | 0.85 | SLC6A7 (0.78) | SLC6A7L3MBTL1ALDH1A1TSHR | |
| SCHEMBL11078057 | 0.83 | SLC6A7 (0.70) | KDM4ESLC6A7MEN1MAPTKMT2A | |
| SCHEMBL6652874 | 0.83 | PKM (0.72) | KDM4ESLC6A7MEN1MAPTKMT2A | |
| SCHEMBL6651764 | 0.83 | ALDH1A1 (0.59) | KDM4ESLC6A7MEN1MAPTKMT2A | |
| SCHEMBL21987023 | 0.82 | MAPT (0.69) | KDM4ESLC6A7MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6656739 | 0.82 | ALDH1A1 (0.58) | KDM4ESLC6A7MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004750-A1 | N-substituted piperazines | PRXL2A, CNPY2, CYP4X1 | KDM4E 280/4885SLC6A7 299/4885MEN1 3085/4885 |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | KDM4E 280/4885SLC6A7 299/4885MEN1 3085/4885 |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | KDM4E 280/4885SLC6A7 299/4885MEN1 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.