SCHEMBL6572943

SCHEMBL6572943

COc1cc(C)c(O)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.59
LMNA P02545 2/20 0.59
PKM P14618 1/20 0.55
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
EP300 Q09472 2/20 0.46
TP53 P04637 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
TSHR P16473 1/20 0.43
IDO1 P14902 1/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
ATM Q13315 2/20 0.42
ALOX15 P16050 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9627412 0.83 EP300 (0.48) HTTLMNAEP300TP53CA1
SCHEMBL5172040 0.82 EP300 (0.47) HTTLMNAEP300TP53CA1
SCHEMBL7622167 0.82 EP300 (0.56) HTTLMNAPTGS2EP300TP53
SCHEMBL17912853 0.79 PKM (0.55) HTTLMNAPKMEP300IDO1
SCHEMBL17912830 0.79 HTT (0.53) HTTLMNAPKMALOX5TP53
SCHEMBL11887380 0.79 IDO1 (0.45) HTTLMNAEP300CA1CA2
SCHEMBL8200684 0.79 LMNA (0.49) HTTLMNAPKMALOX5TSHR
SCHEMBL11075329 0.78 EP300 (0.44) HTTLMNAPKMEP300TP53
SCHEMBL11078452 0.78 ALOX5 (0.50) LMNAPKMALOX5PTGS2EP300
SCHEMBL17787244 0.78 IDO1 (0.55) LMNAPKMALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
US-9060953-B2 1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions THE PROCTER & GAMBLE COMPANY (US) 2015-06-23 US claimed
US-20140289973-A1 1-Hexyl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions WELLA OPERATIONS US, LLC 2014-10-02 US claimed
US-8784505-B2 1-hexzl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions THE PROCTER & GAMBLE COMPANY (US) 2014-07-22 US claimed
EP-2628731-B1 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions PROCTER & GAMBLE (US) 2014-04-23 EP claimed
US-20130212810-A1 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions THE PROCTER & GAMBLE COMPANY (US) 2013-08-22 US claimed
WO-2013122990-A1 1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2013-08-22 WO claimed
EP-2628731-A1 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions The Procter and Gamble Company (US) 2013-08-21 EP claimed
EP-0633501-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-01-11 EP claimed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
EP-4716523-A1 PROCESS FOR PRODUCING HAIR DYES Laboratoire Biosthetique Kosmetik GmbH & Co. KG (DE) 2026-04-01 EP disclosed
EP-4710913-A2 METHOD AND APPARATUS FOR DYEING HAIR FIBRES USING RADIO FREQUENCY ELECTROMAGNETIC RADIATION Jemella Limited (GB) 2026-03-18 EP disclosed
US-12539262-B2 Method for treating freshly bleached hair, composition and use thereof WELLA GERMANY GMBH (DE) 2026-02-03 US disclosed
US-3948958-A Process for making 3-prenylated menaquinones and ether intermediates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1976-04-06 US disclosed
US-3933508-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed
US-3932189-A Thermodevelopable photographic material containing high silver ion conducting substance FUJI PHOTO FILM CO., LTD. (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140289973-A1 1-Hexyl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions PPOX, XDH, DPYD HTT 1198/4885LMNA 2932/4885PKM 2140/4885
US-12539262-B2 Method for treating freshly bleached hair, composition and use thereof KRT18, TYR, CUTA HTT 1080/4885LMNA 727/4885PKM 968/4885
US-20130212810-A1 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions PPOX, XDH, TYR HTT 1390/4885LMNA 2856/4885PKM 2383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.