Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095776 | 0.92 | NPC1 (0.42) | NPC1RAB9AKDM4EKMT2AALDH1A1 | |
| SCHEMBL1107816 | 0.91 | KMT2A (0.36) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL14095777 | 0.84 | SMN1; SMN2 (0.37) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL1107815 | 0.84 | NPC1 (0.40) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL4122181 | 0.81 | NPC1 (0.44) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL1107819 | 0.81 | NPC1 (0.44) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL1107861 | 0.81 | KMT2A (0.37) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL1107807 | 0.79 | NPC1 (0.42) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL1107842 | 0.79 | KMT2A (0.46) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL1107835 | 0.79 | RAB9A (0.46) | NPC1RAB9AKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153560-B2 | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8153560-B2 | Pesticidal active mixtures comprising aminothiazoline compounds | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-20100056469-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100056469-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056469-A1 | Pesticidal Active Mixtures Comprising Aminothiazoline Compounds | ACHE, PTMS, CHRM3 | NPC1 2442/4885RAB9A 2591/4885KDM4E 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.