Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11096481 | 0.97 | OPRM1 (0.44) | OPRM1OPRL1OPRK1HSD11B1PDE2A | |
| SCHEMBL11090584 | 0.85 | OPRM1 (0.66) | OPRM1OPRL1OPRK1HSD11B1PDE2A | |
| SCHEMBL11078629 | 0.80 | OPRL1 (0.51) | OPRM1OPRL1OPRK1HSD11B1MEN1 | |
| SCHEMBL517788 | 0.79 | OPRM1 (0.44) | OPRM1OPRL1OPRK1HSD11B1MEN1 | |
| SCHEMBL4014546 | 0.79 | OPRM1 (0.46) | OPRM1OPRL1OPRK1HSD11B1MEN1 | |
| SCHEMBL4022665 | 0.79 | OPRM1 (0.44) | OPRM1OPRL1OPRK1HSD11B1MEN1 | |
| SCHEMBL517752 | 0.78 | OPRL1 (0.69) | OPRM1OPRL1OPRK1MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL11098093 | 0.77 | OPRM1 (0.42) | OPRM1OPRL1OPRK1HSD11B1MEN1 | |
| SCHEMBL7669838 | 0.77 | MAPT (0.48) | HSD11B1PDE2AMEN1CYP2C9KMT2A | |
| SCHEMBL3404808 | 0.76 | OPRM1 (0.65) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |