Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088655 | 0.82 | ACACB (0.41) | ACACBP2RX3PPARGPPARDPPARA | |
| SCHEMBL11088648 | 0.78 | ACACB (0.48) | ACACBPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL3500467 | 0.75 | ACACB (0.57) | ACACBPARP15PARP10PARP2 | |
| Hydrochloric Acid SCHEMBL3500469 | 0.75 | ACACB (0.57) | ACACBPARP15PARP10PARP2 | |
| SCHEMBL5672844 | 0.74 | LDHA (0.59) | ACACBPPARGPPARA | |
| SCHEMBL7104359 | 0.73 | PARP10 (0.54) | ACACBPARP15PARP10PARP2 | |
| SCHEMBL11084088 | 0.73 | THRB (0.50) | ACACBPPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL3498383 | 0.72 | PARP10 (0.53) | ACACBPARP15PARP10PARP2 | |
| Hydrochloric Acid SCHEMBL3498380 | 0.72 | PARP10 (0.53) | ACACBPARP15PARP10PARP2 | |
| SCHEMBL11084084 | 0.72 | ACACB (0.43) | ACACBPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461902-A | BLOOD LIPID AND SUGAR LOWERING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-07-24 | — | — | US | disclosed |
| EP-0084926-A1 | Thiazolidine derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-08-03 | — | — | EP | disclosed |