Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081798 | 0.99 | MCL1 (0.41) | MCL1KDM4EHAO1ALDH1A1MAPT | |
| SCHEMBL11082665 | 0.94 | CREBBP (0.37) | MCL1KDM4EHAO1ALDH1A1MAPT | |
| SCHEMBL6294299 | 0.81 | MCL1 (0.38) | MCL1KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5049361 | 0.79 | PTGDR2 (0.48) | KDM4ENAAAF2RL1EPHX2PTGDR2 | |
| SCHEMBL5051928 | 0.79 | PTGDR2 (0.48) | KDM4ENAAAF2RL1EPHX2PTGDR2 | |
| SCHEMBL15477730 | 0.78 | MCL1 (0.43) | MCL1KDM4EALDH1A1 | |
| SCHEMBL3664492 | 0.78 | MCL1 (0.38) | MCL1KDM4EHAO1ALDH1A1MAPT | |
| SCHEMBL3979460 | 0.77 | PTGDR2 (0.45) | KDM4ENAAAF2RL1EPHX2PTGDR2 | |
| SCHEMBL9699947 | 0.77 | MCL1 (0.44) | MCL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5051903 | 0.76 | PTGDR2 (0.44) | KDM4ENAAAF2RL1EPHX2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460600-A | Adjacently substituted ketal derivatives of cycloalkane-amide analgesics | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |