Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079196 | 0.99 | MCL1 (0.40) | MCL1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL11082665 | 0.96 | CREBBP (0.37) | MCL1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL6294299 | 0.82 | MCL1 (0.38) | MCL1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL3664492 | 0.79 | MCL1 (0.38) | MCL1KDM4EMAPTALDH1A1HAO1 | |
| SCHEMBL3979460 | 0.79 | PTGDR2 (0.45) | KDM4EMAPT | |
| SCHEMBL9699947 | 0.78 | MCL1 (0.44) | MCL1KDM4EALDH1A1CREBBP | |
| Hydrochloric Acid SCHEMBL5051903 | 0.77 | PTGDR2 (0.44) | KDM4EMAPT | |
| SCHEMBL5049361 | 0.77 | PTGDR2 (0.48) | KDM4EMAPT | |
| SCHEMBL5051928 | 0.77 | PTGDR2 (0.48) | KDM4EMAPT | |
| SCHEMBL15477730 | 0.77 | MCL1 (0.43) | MCL1KDM4EALDH1A1CREBBPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460600-A | Adjacently substituted ketal derivatives of cycloalkane-amide analgesics | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |