Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382948 | 0.81 | ALDH1A1 (0.41) | TSHRRAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL10384782 | 0.78 | OPRM1 (0.40) | TSHRALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL10618369 | 0.76 | TSHR (0.55) | TSHRL3MBTL1TDP1THRBTP53 | |
| SCHEMBL10383421 | 0.75 | HDAC1 (0.39) | TSHRTP53RAB9AALDH1A1KMT2A | |
| SCHEMBL4581875 | 0.75 | TSHR (0.40) | TSHRL3MBTL1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL8284019 | 0.74 | TSHR (0.53) | TSHRL3MBTL1TDP1THRBTP53 | |
| SCHEMBL17675195 | 0.74 | TSHR (0.59) | TSHRL3MBTL1THRBTP53RAB9A | |
| SCHEMBL5225088 | 0.74 | TSHR (0.59) | TSHRL3MBTL1THRBTP53RAB9A | |
| SCHEMBL11610217 | 0.73 | TSHR (0.41) | TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10382984 | 0.73 | HDAC6 (0.40) | SMN1; SMN2KMT2AMEN1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451653-A | INSECTICIDCES | THE DOW CHEMICAL COMPANY (US) | 1984-05-29 | — | — | US | disclosed |
| US-4433148-A | CHEMICAL INTERMEDIATES FOR TRIAZOLYL PHOSPHORUS INSECTICIDWS | THE DOW CHEMICAL CO. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4400516-A | PYRIDINE OR QUINOLINE SUBSTITUTED PESTICIDES | THE DOW CHEMICAL CO. (US) | 1983-08-23 | — | — | US | disclosed |
| US-4357327-A | Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides | THE DOW CHEMICAL CO. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4357328-A | Heterocyclic substituted triazolyl phosphorous compounds and their use as insecticides | THE DOW CHEMICAL CO. (US) | 1982-11-02 | — | — | US | disclosed |
| EP-0010891-B1 | HETEROCYCLIC SUBSTITUTED TRIAZOLYL PHOSPHOROUS COMPOUNDS, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHOD FOR CONTROLLING INSECTS | THE DOW CHEMICAL COMPANY (US) | 1982-09-01 | — | — | EP | disclosed |
| US-4298602-A | MITICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0010891-A1 | Heterocyclic substituted triazolyl phosphorous compounds, insecticidal compositions containing them and method for controlling insects | THE DOW CHEMICAL COMPANY (US) | 1980-05-14 | — | — | EP | disclosed |