Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112509 | 0.82 | FAAH (0.55) | FAAHBCHE | |
| SCHEMBL27182064 | 0.82 | PTGDR2 (0.48) | CASP3SENP8SENP7SENP6GAA | |
| SCHEMBL8112175 | 0.82 | FAAH (0.55) | FAAHBCHE | |
| SCHEMBL27157063 | 0.81 | PTGDR2 (0.47) | CASP3SENP8SENP7SENP6FAAH | |
| SCHEMBL31269654 | 0.81 | BCHE (0.47) | CASP3SENP8SENP7SENP6FAAH | |
| SCHEMBL27152451 | 0.78 | ALDH1A1 (0.49) | PTGDR2AKR1B10BCHE | |
| SCHEMBL8008240 | 0.78 | KDM4E (0.63) | GAATEKBCHE | |
| SCHEMBL7996428 | 0.75 | KDM4E (0.53) | GAATEKBCHE | |
| SCHEMBL8104149 | 0.75 | FAAH (0.70) | FAAHGAABCHE | |
| SCHEMBL8104170 | 0.75 | FAAH (0.70) | FAAHGAABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424229-A | ANALGESICS | A/S DUMEX (DUMEX LTD.) (DK) | 1984-01-03 | — | — | US | disclosed |
| EP-0005219-B1 | ARYLIMIDAZOLES, THEIR SYNTHESIS AND PHARMACEUTICAL OR VETERINARY PREPARATIONS CONTAINING THEM | A/S Dumex (Dumex Ltd.) (DK) | 1981-07-22 | — | — | EP | disclosed |
| EP-0005219-A1 | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them | A/S Dumex (Dumex Ltd.) (DK) | 1979-11-14 | — | — | EP | disclosed |