Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12744034 | 0.86 | CYP2C9 (0.41) | TSHRCYP2C9APPSMN1; SMN2 | |
| SCHEMBL477080 | 0.85 | PARL (0.38) | TSHRPARLAPPPSIP1POLB | |
| SCHEMBL11128744 | 0.84 | PARL (0.38) | PARLAPPPSIP1POLBRAB9A | |
| SCHEMBL11088598 | 0.84 | MAPK1 (0.40) | TSHRPARLAPPRAB9AMAPK1 | |
| SCHEMBL11082873 | 0.80 | CA1 (0.40) | CYP2C9PARLHSD11B1 | |
| SCHEMBL27374807 | 0.80 | PSIP1 (0.41) | PARLPSIP1POLBRAB9AMAPK1 | |
| SCHEMBL11081257 | 0.79 | APP (0.46) | PARLAPPPSIP1POLBRAB9A | |
| SCHEMBL11079290 | 0.78 | SMN1; SMN2 (0.57) | TSHRCYP2C9PSIP1POLBRAB9A | |
| SCHEMBL476991 | 0.78 | CYP1A2 (0.41) | TSHRPARLPSIP1MAPK1SMN1; SMN2 | |
| SCHEMBL476994 | 0.78 | PARL (0.42) | TSHRPARLPSIP1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050327-B1 | PHOSPHOLIPIDS THAT CONTAIN SULPHUR, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1984-06-20 | — | — | EP | disclosed |
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |
| EP-0050327-A1 | Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1982-04-28 | — | — | EP | disclosed |