Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476994 | 0.90 | PARL (0.42) | PARLTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL11079288 | 0.85 | TSHR (0.42) | PARLTSHRSMN1; SMN2MAPTRAB9A | |
| SCHEMBL3446919 | 0.84 | STAT3 (0.41) | SMN1; SMN2ALDH1A1KMT2AGAACYP2C19 | |
| SCHEMBL14778018 | 0.83 | PSIP1 (0.41) | PARLSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL11128744 | 0.83 | PARL (0.38) | PARLSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL2058342 | 0.82 | PARL (0.37) | PARLSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL11082873 | 0.81 | CA1 (0.40) | PARLALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL2057643 | 0.80 | PARL (0.35) | PARLSMN1; SMN2TDP1ALDH1A1KDM4E | |
| SCHEMBL476991 | 0.79 | CYP1A2 (0.41) | PARLTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL11088598 | 0.79 | MAPK1 (0.40) | PARLTSHRSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807339-A1 | TRANSESTERIFICATION METHOD FOR SIMULTANEOUSLY PRODUCING AT LEAST TWO DIFFERENT POLYCARBONATES IN A PRODUCTION FACILITY | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238419-A1 | TRANSESTERIFICATION METHOD FOR SIMULTANEOUSLY PRODUCING AT LEAST TWO DIFFERENT POLYCARBONATES IN A PRODUCTION FACILITY | COVESTRO DEUTSCHLAND AG (DE) | 2019-12-19 | — | — | WO | disclosed |
| EP-2147038-B1 | METHOD FOR THE PRODUCTION OF POLYCARBONATE ACCORDING TO A MELT TRANSESTERIFICATION PROCESS | BAYER IP GMBH (DE) | 2015-07-01 | — | — | EP | disclosed |
| EP-2058363-B1 | Method of manufacturing polycarbonate using the melting ester interchange method | BAYER MATERIALSCIENCE AG (DE) | 2012-02-01 | — | — | EP | disclosed |
| US-7814626-B2 | Process for the preparation of polycarbonate by the melt transesterification process | BAYER MATERIALSCIENCE AG (DE) | 2010-10-19 | — | — | US | disclosed |
| EP-2147038-A2 | METHOD FOR THE PRODUCTION OF POLYCARBONATE ACCORDING TO A MELT TRANSESTERIFICATION PROCESS | Bayer MaterialScience AG (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-2058363-A1 | Method of manufacturing polycarbonate using the melting ester interchange method | Bayer MaterialScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-20080319156-A1 | Process For The Preparation Of Polycarbonate By The Melt Transesterification Process | BAYER MATERIALSCIENCE AG (DE) | 2008-12-25 | — | — | US | disclosed |
| WO-2008138517-A2 | METHOD FOR THE PRODUCTION OF POLYCARBONATE ACCORDING TO A MELT TRANSESTERIFICATION PROCESS | BAYER MATERIALSCIENCE AG (DE) | 2008-11-20 | — | — | WO | disclosed |