Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646333 | 0.86 | DGKA (0.50) | DGKADNM1L3MBTL1MAPTPAM | |
| SCHEMBL10011139 | 0.85 | DGKA (0.50) | DGKADNM1L3MBTL1MAPTMAPK1 | |
| SCHEMBL19638 | 0.84 | DGKA (0.67) | DGKADNM1L3MBTL1MAPTMAPK1 | |
| SCHEMBL30861849 | 0.83 | DGKA (0.62) | DGKADNM1L3MBTL1MAPTPAM | |
| SCHEMBL16907300 | 0.82 | — | — | |
| SCHEMBL21891949 | 0.82 | DGKA (0.71) | DGKADNM1L3MBTL1MAPTMAPK1 | |
| SCHEMBL10011190 | 0.81 | DGKA (0.55) | DGKADNM1L3MBTL1MAPTMAPK1 | |
| SCHEMBL10010056 | 0.81 | L3MBTL1 (0.59) | DGKADNM1L3MBTL1MAPTMAPK1 | |
| SCHEMBL9351362 | 0.80 | DGKA (0.58) | DGKADNM1L3MBTL1MAPTPAM | |
| SCHEMBL9355444 | 0.80 | DGKA (0.58) | DGKADNM1L3MBTL1MAPTPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436828-A | Reactive asymmetrical dicarboxylic acid esters and reagents for the investigation of cardiac glycosides | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-13 | — | — | US | disclosed |
| US-4282151-A | Reactive asymmetrical dicarboxylic acid esters and reagents for the investigation of cardiac glycosides | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |
| US-4133949-A | Dicarboxylic acid esters of cardiac glycosides | BOEHRINGER MANNHEIM GMBH (DE) | 1979-01-09 | — | — | US | disclosed |