Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082282 | 0.73 | CYP3A4 (0.39) | MAPTLMNAKDM4EALDH1A1CYP2D6 | |
| SCHEMBL11080939 | 0.72 | SLC6A3 (0.37) | SLC6A3SLC6A4SMN1; SMN2ADRA2AADRA2B | |
| SCHEMBL6568570 | 0.72 | KDM1A (0.53) | SLC6A3SLC6A4CHRNA7 | |
| SCHEMBL11086002 | 0.72 | KDM4C (0.35) | SLC6A3SLC6A4NPC1MAPTRAB9A | |
| SCHEMBL3896827 | 0.72 | SIGMAR1 (0.36) | TAAR1ALDH1A1 | |
| SCHEMBL3910550 | 0.72 | KDM1A (0.53) | SLC6A3SLC6A4 | |
| SCHEMBL30558325 | 0.71 | APP (0.39) | MAPT | |
| SCHEMBL17361959 | 0.71 | APP (0.39) | MAPT | |
| SCHEMBL1333907 | 0.69 | KDM1A (0.47) | CYP2D6 | |
| SCHEMBL6567499 | 0.69 | KDM1A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473586-A | Aminoalkyl dihydronaphthalenes | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | disclosed |