Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079385 | 0.72 | SLC6A3 (0.42) | SLC6A3SLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL11083684 | 0.67 | PARP1 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL11080380 | 0.66 | HTR2A (0.40) | ALDH1A1 | |
| SCHEMBL17397905 | 0.66 | SLC6A3 (0.35) | SLC6A3SLC6A4AOC3 | |
| SCHEMBL20957868 | 0.65 | MTNR1A (0.34) | AOC3ALDH1A1KMT2ASMN1; SMN2XBP1 | |
| SCHEMBL20478688 | 0.65 | MTNR1A (0.34) | AOC3ALDH1A1KMT2ASMN1; SMN2XBP1 | |
| SCHEMBL20478829 | 0.65 | MTNR1A (0.34) | AOC3ALDH1A1KMT2ASMN1; SMN2XBP1 | |
| SCHEMBL7565934 | 0.65 | ALDH1A1 (0.42) | DRD2ALDH1A1KMT2A | |
| SCHEMBL1333907 | 0.63 | KDM1A (0.47) | DRD2KMT2A | |
| SCHEMBL11079535 | 0.63 | AR (0.38) | SLC6A3SLC6A4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473586-A | Aminoalkyl dihydronaphthalenes | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | disclosed |