Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | GLA | P06280 | 5/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075633 | 0.82 | KDM4E (0.70) | KDM4EMAPTHSD17B10UBE2NHTT | |
| SCHEMBL11080686 | 0.81 | KDM4E (0.52) | KDM4EMAPTHSD17B10UBE2NHTT | |
| SCHEMBL10975250 | 0.77 | PDE5A (0.66) | KDM4EMAPTMEN1KMT2AHPGD | |
| SCHEMBL11075853 | 0.76 | KDM4E (0.49) | KDM4EMAPTHSD17B10UBE2NHTT | |
| SCHEMBL10508426 | 0.76 | PDE5A (0.53) | KDM4EMAPTHSD17B10GAAALDH1A1 | |
| SCHEMBL11079352 | 0.75 | GAA (0.63) | KDM4EMAPTHSD17B10GAAGLA | |
| SCHEMBL10687608 | 0.73 | MEN1 (0.46) | KDM4EMAPTMCL1POLBMEN1 | |
| SCHEMBL11066769 | 0.72 | ABCB11 (0.49) | KDM4EMAPTHSD17B10UBE2NGAA | |
| SCHEMBL11066632 | 0.72 | KDM4E (0.61) | KDM4EMAPTHSD17B10HTTGAA | |
| SCHEMBL10404717 | 0.71 | KDM4E (0.64) | KDM4EMAPTHSD17B10UBE2NGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |