Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Probicromil SCHEMBL371493 | 0.89 | PDE5A (0.55) | ABCB11PDE5AKMT2AHPGDMAPT | |
| Probicromil SCHEMBL11378747 | 0.88 | PDE5A (0.54) | ABCB11PDE5AKMT2AHPGDMAPT | |
| SCHEMBL10506749 | 0.83 | PDE5A (0.50) | ABCB11PDE5AKMT2AHPGDMAPT | |
| SCHEMBL11071974 | 0.83 | KDM4E (0.57) | KMT2AHPGDMAPTMEN1KDM4E | |
| SCHEMBL10507452 | 0.82 | PDE5A (0.50) | ABCB11PDE5AKMT2AHPGDMAPT | |
| SCHEMBL11066772 | 0.82 | LMNA (0.41) | KMT2AHPGDMAPTMEN1KDM4E | |
| SCHEMBL10507005 | 0.82 | PDE5A (0.53) | ABCB11PDE5AKMT2AHPGDMAPT | |
| SCHEMBL11071258 | 0.81 | ABCB11 (0.47) | ABCB11PDE5AKMT2AHPGDMAPT | |
| SCHEMBL11185883 | 0.80 | ABCB11 (0.45) | ABCB11PDE5AKMT2AHPGDMAPT | |
| SCHEMBL10504791 | 0.78 | PDE5A (0.48) | ABCB11PDE5AKMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | claimed |
| EP-0108036-A1 | Benzopyranones | CIBA-GEIGY AG (CH) | 1984-05-09 | — | — | EP | disclosed |