Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | PNMT | P11086 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080380 | 0.73 | HTR2A (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL11079530 | 0.71 | AR (0.38) | ARPNMTSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11079679 | 0.69 | KDM1A (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL11568059 | 0.66 | HTR2A (0.38) | ARPNMTHTR2AHTR2CHTR2B | |
| SCHEMBL22254519 | 0.64 | SLC6A3 (0.35) | ARSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL11083684 | 0.63 | PARP1 (0.41) | — | |
| SCHEMBL3910550 | 0.62 | KDM1A (0.53) | SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL7565934 | 0.61 | ALDH1A1 (0.42) | HTR2A | |
| SCHEMBL8613008 | 0.61 | AR (0.33) | ARSLC6A3SLC6A4 | |
| SCHEMBL11086002 | 0.58 | KDM4C (0.35) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473586-A | Aminoalkyl dihydronaphthalenes | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | disclosed |