Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333907 | 0.90 | KDM1A (0.47) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL19130231 | 0.79 | KDM1A (0.47) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL7960703 | 0.79 | KDM1A (0.44) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL6691850 | 0.79 | KDM1A (0.47) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL9499577 | 0.79 | KDM1A (0.46) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL4420303 | 0.77 | SIGMAR1 (0.49) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL15891588 | 0.75 | CASP6 (0.45) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL18428569 | 0.75 | KDM1A (0.50) | KDM1AMEN1KMT2AHTR2ASIGMAR1 | |
| SCHEMBL8255088 | 0.75 | LMNA (0.58) | KDM1AHTR2ASIGMAR1CYP2D6HTR2C | |
| SCHEMBL9501252 | 0.75 | KDM1A (0.41) | KDM1AMEN1KMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473586-A | Aminoalkyl dihydronaphthalenes | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | disclosed |