Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430260 | 0.94 | DPP4 (0.49) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL11009027 | 0.90 | CTRB1 (0.55) | PREPCTRB1KMT2APRCPCYP3A4 | |
| SCHEMBL29388202 | 0.89 | PREP (0.51) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL27543280 | 0.87 | DPP4 (0.45) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL22209369 | 0.86 | MALT1 (0.50) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL27559428 | 0.86 | PREP (0.44) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL18873440 | 0.83 | PREP (0.45) | PREPDPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL18831927 | 0.82 | PREP (0.44) | PREPDPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL18831929 | 0.82 | PREP (0.44) | PREPDPP4DPP8DPP9DPP7 | |
| SCHEMBL2192304 | 0.81 | OPRM1 (0.49) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463090-A | PROENZYMES COUPLED TO LIGANDS; ACTIVATION; SENSITIVITY | RAPIDEX LIMITED | 1984-07-31 | — | — | US | disclosed |