Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559428 | 0.88 | PREP (0.44) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL11009027 | 0.88 | CTRB1 (0.55) | PREPCTRB1PRCP | |
| SCHEMBL11430260 | 0.87 | DPP4 (0.49) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL11079609 | 0.87 | PREP (0.51) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL29872221 | 0.86 | DPP4 (0.52) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL11013687 | 0.84 | F2 (0.60) | ACEPRSS1F2 | |
| SCHEMBL11013694 | 0.84 | F2 (0.60) | ACEPRSS1F2 | |
| SCHEMBL9280512 | 0.84 | XIAP (0.48) | EPHA2PRSS1F2 | |
| SCHEMBL7207928 | 0.83 | OPRM1 (0.51) | ACEEPHA2PRSS1F2 | |
| SCHEMBL9450497 | 0.83 | DPP4 (0.47) | DPP4DPP8DPP7DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1313863-A | Inhibitors of urokinase and angiogenesis | CORVAS INTERNAT INC (US) | 2001-09-19 | — | — | CN | disclosed |