Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085842 | 0.84 | MAPT (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10929004 | 0.77 | MAPT (0.56) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11090465 | 0.73 | MAPT (0.45) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL11087922 | 0.72 | TSHR (0.41) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL1347263 | 0.68 | CRBN (0.46) | ALDH1A1MAPTKMT2AGAALMNA | |
| SCHEMBL29576353 | 0.67 | ALDH1A1 (0.46) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11153665 | 0.65 | ALDH1A1 (0.47) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10927787 | 0.65 | GABRP (0.64) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17479578 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AGAALMNA | |
| SCHEMBL30100756 | 0.65 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464300-A | PSYCHOTROPIC, ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1984-08-07 | — | — | US | disclosed |