Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090465 | 0.88 | MAPT (0.45) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL11079648 | 0.84 | ALDH1A1 (0.50) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL11087922 | 0.77 | TSHR (0.41) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL8117192 | 0.77 | MAPT (0.60) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL11083785 | 0.75 | CHRM1 (0.41) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL10929981 | 0.74 | MAPT (0.77) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL869274 | 0.71 | TP53 (1.00) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL31071906 | 0.71 | TP53 (1.00) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL28355878 | 0.70 | MAPT (0.56) | MAPTTP53CYP1A2CYP2C9ALOX15 | |
| SCHEMBL5435436 | 0.69 | MAPT (0.56) | MAPTTP53CYP1A2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464300-A | PSYCHOTROPIC, ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1984-08-07 | — | — | US | disclosed |