Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.45 |
| ▸ | CTSL | P07711 | 12/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.44 |
| ▸ | CTSB | P07858 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546367 | 0.92 | CTSK (0.43) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL11285887 | 0.89 | CTSL (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10544718 | 0.87 | CASP3 (0.47) | CTSKCTSLCTSSCTSBCASP1 | |
| Pyridine SCHEMBL10543547 | 0.85 | CTSL (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL10682244 | 0.85 | ATM (0.59) | CTSKCTSLCTSS | |
| SCHEMBL10541108 | 0.84 | CTSK (0.43) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL11080515 | 0.83 | CTSK (0.47) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL10541088 | 0.82 | CTSL (0.65) | CTSKCTSLCTSS | |
| SCHEMBL11075371 | 0.82 | XIAP (0.35) | — | |
| SCHEMBL11080042 | 0.80 | CTSL (0.44) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021678-B1 | 1-SULPHO-2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1984-11-07 | — | — | EP | disclosed |