Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 5/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088100 | 0.84 | GABRA1 (0.48) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11082815 | 0.80 | GABRA1 (0.67) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11084794 | 0.77 | GABRA1 (0.49) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11082165 | 0.75 | HPGD (0.44) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11083107 | 0.73 | HPGD (0.43) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11087109 | 0.71 | GABRA5 (0.43) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11081745 | 0.71 | MEN1 (0.37) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11838601 | 0.70 | GABRA1 (0.71) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11705443 | 0.68 | GABRA1 (0.76) | GABRA5GABRA1GABRA2GABRB2GABRA3 | |
| SCHEMBL11603285 | 0.67 | GABRA1 (0.74) | GABRA5GABRA1GABRA2GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464300-A | PSYCHOTROPIC, ANXIOLYTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1984-08-07 | — | — | US | disclosed |