Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 6/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086388 | 1.00 | ADRA1A (0.58) | ADRA1AADRA1DADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11080879 | 0.99 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11086750 | 0.99 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL11080140 | 0.99 | ADRA1A (0.59) | ADRA1AADRA1DADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL11079693 | 0.98 | ADRA1A (0.58) | ADRA1AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL11086815 | 0.88 | HTR1A (0.68) | HTR1ADRD2HTR7HTR1DHTR1B | |
| SCHEMBL11029655 | 0.88 | HTR1A (0.68) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL11082872 | 0.87 | HTR1A (0.67) | HTR1ADRD2HTR7HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL11089984 | 0.87 | HTR1A (0.67) | HTR1ADRD2HTR7HTR1DHTR1B | |
| SCHEMBL11080260 | 0.87 | HTR1A (0.67) | HTR1ADRD2HTR7HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438115-A | PIPERAZINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0042162-B1 | COMPOSITIONS FOR TREATING DISEASES IN CIRCULATORY ORGANS | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-11-23 | — | — | EP | disclosed |
| EP-0042162-A2 | Compositions for treating diseases in circulatory organs | Chugai Seiyaku Kabushiki Kaisha (JP) | 1981-12-23 | — | — | EP | disclosed |