Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079859 | 0.88 | ESR2 (0.48) | ESR1ESR2TTRCA2ALOX12 | |
| SCHEMBL11112282 | 0.70 | CYP19A1 (0.40) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL11080196 | 0.69 | KDM4E (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL1192912 | 0.67 | CYP3A4 (0.45) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL29790627 | 0.67 | CYP3A4 (0.45) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL8885769 | 0.66 | PTGS1 (0.44) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL25193522 | 0.64 | AR (0.42) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL25265067 | 0.64 | AR (0.42) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL20005271 | 0.64 | CYP3A4 (0.41) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL5738218 | 0.62 | ALDH1A1 (0.37) | ESR1ESR2TTRALOX12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436749-A | CARDIOVASCULAR DISORDERS | PIERRE FABRE S.A. (FR) | 1984-03-13 | — | — | US | disclosed |