Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076881 | 0.83 | CYP19A1 (0.49) | CYP19A1TSHRLMNAMAPTALDH1A1 | |
| SCHEMBL9636409 | 0.74 | NISCH (0.36) | CYP19A1NISCHMEN1MAPTKMT2A | |
| SCHEMBL7927222 | 0.72 | HTT (0.39) | CYP19A1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10601545 | 0.70 | RAB9A (0.33) | CYP19A1NISCHLMNAALDH1A1NPC1 | |
| SCHEMBL11079859 | 0.70 | ESR2 (0.48) | CYP19A1 | |
| SCHEMBL11080196 | 0.70 | KDM4E (0.42) | MEN1MAPTKMT2AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10603135 | 0.69 | POLB (0.34) | CYP19A1LMNAALDH1A1NPC1HPGD | |
| SCHEMBL30315348 | 0.68 | NFKB1 (0.38) | CYP19A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL725410 | 0.68 | NFKB1 (0.38) | CYP19A1TSHRMEN1MAPTKMT2A | |
| SCHEMBL17229229 | 0.68 | NFKB1 (0.38) | CYP19A1TSHRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436749-A | CARDIOVASCULAR DISORDERS | PIERRE FABRE S.A. (FR) | 1984-03-13 | — | — | US | disclosed |