Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.48 |
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | YES1 | P07947 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080392 | 0.88 | ESR1 (0.44) | ESR2ESR1TTRCA2ALOX12 | |
| SCHEMBL11080196 | 0.78 | KDM4E (0.42) | CA2 | |
| SCHEMBL31110641 | 0.72 | NFKB1 (0.43) | ESR2ESR1TTRCA2CA5A | |
| SCHEMBL30800496 | 0.72 | NFKB1 (0.43) | ESR2ESR1TTRCA2CA5A | |
| SCHEMBL31110640 | 0.72 | NFKB1 (0.43) | ESR2ESR1TTRCA2CA5A | |
| SCHEMBL11073047 | 0.71 | ALOX15 (0.39) | CA2CA5AALOX12ALOX15CYP19A1 | |
| SCHEMBL547263 | 0.67 | STS (0.49) | ESR2ESR1TTRCA2CA5A | |
| SCHEMBL29771885 | 0.67 | STS (0.49) | ESR2ESR1TTRCA2CA5A | |
| SCHEMBL11080406 | 0.66 | CYP19A1 (0.46) | CA2CA5ACYP3A4CYP19A1 | |
| SCHEMBL18721922 | 0.66 | CA2 (0.43) | ESR2ESR1CA2CA5AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436749-A | CARDIOVASCULAR DISORDERS | PIERRE FABRE S.A. (FR) | 1984-03-13 | — | — | US | disclosed |