Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073931 | 0.97 | SPHK1 (0.39) | SPHK1ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11078904 | 0.91 | SLC1A3 (0.34) | SPHK1SPHK2 | |
| SCHEMBL11078190 | 0.88 | ABCB11 (0.34) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11068024 | 0.85 | NAAA (0.34) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11074120 | 0.84 | NAAA (0.37) | — | |
| SCHEMBL11076967 | 0.83 | NAAA (0.36) | ABCB11 | |
| SCHEMBL11070066 | 0.83 | SPHK1 (0.44) | SPHK1ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11069034 | 0.82 | ABCB11 (0.54) | SPHK1ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11071353 | 0.82 | ABCB11 (0.38) | ABCB11LMNAMAPTMAPK1 | |
| SCHEMBL11076113 | 0.82 | ABCB11 (0.34) | ABCB11LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |