Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077273 | 0.83 | HTR2A (0.39) | ACHENOTUM | |
| SCHEMBL11084848 | 0.82 | ACHE (0.51) | ACHENOTUMDPP4DPP8DPP9 | |
| SCHEMBL11088030 | 0.80 | ACHE (0.49) | ACHEDPP4DPP8DPP9DPP7 | |
| SCHEMBL11079796 | 0.79 | PNMT (0.42) | ACHEBCHE | |
| SCHEMBL11082337 | 0.74 | METAP1 (0.47) | ACHENOTUM | |
| SCHEMBL11219735 | 0.74 | METAP1 (0.47) | ACHEPARP10 | |
| SCHEMBL28390141 | 0.74 | ACHE (0.58) | ACHEPARP1PARP10NOS3KMT2A | |
| SCHEMBL29443084 | 0.72 | ACHE (0.56) | ACHEKMT2A | |
| SCHEMBL4015424 | 0.72 | ACHE (0.56) | ACHEKMT2A | |
| SCHEMBL29443082 | 0.72 | ACHE (0.56) | ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | claimed |
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | disclosed |