Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 3/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617648 | 0.85 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL11080595 | 0.79 | ACHE (0.55) | ACHEBCHE | |
| SCHEMBL11077273 | 0.79 | HTR2A (0.39) | HTR1ADRD2HTR2AHTTACHE | |
| SCHEMBL12237094 | 0.78 | HTR1A (0.41) | PNMTADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL8667324 | 0.76 | PNMT (0.52) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2246368 | 0.75 | ACHE (0.58) | PNMTADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL15617650 | 0.75 | TLR9 (0.46) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL12237175 | 0.74 | HTR1A (0.41) | PNMTADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL1808330 | 0.72 | PTPRC (0.47) | PNMTADRA2AADRA2BADRA2CHTR1A | |
| SCHEMBL10854713 | 0.71 | TDP2 (0.45) | PNMTADRA2AADRA2BADRA2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | claimed |
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | disclosed |