Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339033 | 0.82 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL6258179 | 0.79 | CA1 (0.39) | SLC6A2SLC6A4TEAD1MAOB | |
| SCHEMBL7154266 | 0.77 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3NPC1MAOB | |
| SCHEMBL31707544 | 0.75 | ACHE (0.50) | SLC6A2SLC6A4SLC6A3L3MBTL1TP53 | |
| SCHEMBL19308535 | 0.74 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3L3MBTL1KMT2A | |
| SCHEMBL15627282 | 0.74 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3L3MBTL1KMT2A | |
| SCHEMBL20858622 | 0.74 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3L3MBTL1KMT2A | |
| SCHEMBL24727287 | 0.73 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3L3MBTL1KMT2A | |
| SCHEMBL83664 | 0.73 | SLC6A4 (0.64) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL167016 | 0.72 | L3MBTL1 (0.58) | L3MBTL1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447428-A | BRONCHODILATOR, ANTICOAGULANTS | GLAXO GROUP LIMITED (GB) | 1984-05-08 | — | — | US | disclosed |
| US-4409213-A | B-SIDE CHAIN ATTACHED THRU AMINO GROUP; BRONCHODILATORS, ANTICOAGUANT | GLAXO GROUP LIMITED (GB) | 1983-10-11 | — | — | US | disclosed |
| US-4265891-A | PROSTAGLANDINS, BRONCHODILATORS, PLATELET AGGREGATION INHIBITORS | GLAXO GROUP LIMITED (GB) | 1981-05-05 | — | — | US | disclosed |