Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821064 | 0.84 | HPGD (0.45) | HPGDTACR3ALOX5KMT2ACES2 | |
| SCHEMBL27965725 | 0.81 | HPGD (0.45) | HPGDTACR3ALOX5KMT2ACES2 | |
| SCHEMBL10585597 | 0.74 | PTGS1 (0.42) | HPGDTACR3ALOX5KMT2AKDM4E | |
| SCHEMBL5179018 | 0.74 | ALDH1A1 (0.45) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL791595 | 0.73 | IDO1 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL5542458 | 0.73 | HPGD (0.48) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9328003 | 0.73 | ALOX5 (0.47) | HPGDTACR3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2370589 | 0.73 | HPGD (0.55) | HPGDTACR3ALOX5KMT2ACES2 | |
| SCHEMBL12895886 | 0.73 | HPGD (0.55) | HPGDTACR3ALOX5KMT2ACES2 | |
| SCHEMBL9000694 | 0.73 | CES2 (0.56) | HPGDTACR3ALOX5KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002846-B1 | 3-THIENYLMALONIC ACIDS, THE CORRESPONDING DIESTERS AND THEIR PREPARATION | Océ-Andeno B.V. (NL) | 1984-05-23 | — | — | EP | disclosed |