SCHEMBL1108080

SCHEMBL1108080

CCCCCCCCC(CCCCCC)COc1cc(SOOO)ccc1OCCOCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108074 0.93 USP2 (0.36) USP2MAPTTSHR
SCHEMBL1108073 0.93 MAPT (0.35) USP2MAPTTSHR
SCHEMBL1108092 0.86 MAPT (0.39) USP2MAPTTSHR
SCHEMBL9915557 0.72 SMPD1 (0.42) MAPT
SCHEMBL1108111 0.66 MAPT (0.41) USP2MAPTTSHR
SCHEMBL1108101 0.66 MAPT (0.41) USP2MAPTTSHR
SCHEMBL9587375 0.64 TSHR (0.40) USP2MAPTTSHR
SCHEMBL9588956 0.61 CYP1A2 (0.40) USP2MAPTTSHR
SCHEMBL9728727 0.60 MAPT (0.40) USP2MAPTTSHR
SCHEMBL14565990 0.59 THRB (0.40) USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed