SCHEMBL1108074

SCHEMBL1108074

CCCCCCCCC(CCCCCC)COc1cc(SOOO)ccc1OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1108080 0.93 USP2 (0.32) USP2MAPTTSHR
SCHEMBL1108092 0.90 MAPT (0.39) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL1108073 0.84 MAPT (0.35) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL9915557 0.70 SMPD1 (0.42) MAPT
SCHEMBL1108094 0.63 MAPT (0.48) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL1108076 0.63 MAPT (0.48) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL14282534 0.62 MAPT (0.44) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL13612648 0.62 MAPT (0.44) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL13612654 0.62 MAPT (0.44) USP2MAPTTSHRCYP1A2CYP2C9
SCHEMBL13713341 0.60 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed