Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108073 | 0.94 | MAPT (0.35) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL1108080 | 0.86 | USP2 (0.32) | MAPTUSP2TSHR | |
| SCHEMBL9915557 | 0.81 | SMPD1 (0.42) | MAPTS1PR1LMNATHRATHRB | |
| SCHEMBL1108076 | 0.66 | MAPT (0.48) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL1108102 | 0.66 | MAPT (0.48) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL1108094 | 0.66 | MAPT (0.48) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL13612648 | 0.65 | MAPT (0.44) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL14282534 | 0.65 | MAPT (0.44) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL13612654 | 0.65 | MAPT (0.44) | MAPTUSP2TSHRCYP1A2CYP2C19 | |
| SCHEMBL14340948 | 0.65 | NAAA (0.34) | MAPTUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153246-B2 | Optical compensatory film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-7658864-B2 | Liquid crystal composition, optical compensation film and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20090273740-A1 | OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2009-11-05 | — | — | US | disclosed |
| US-20090009693-A1 | Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device | FUJIFILM CORPORATION (JP) | 2009-01-08 | — | — | US | disclosed |