SCHEMBL1108081

SCHEMBL1108081

CCCNS(=O)(=O)c1cccc(NC(C)=O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.57
ALDH1A1 P00352 4/20 0.57
MAPT P10636 1/20 0.57
PKM P14618 1/20 0.56
NR4A1 P22736 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HSD17B10 Q99714 2/20 0.48
TSHR P16473 1/20 0.48
CYP1A2 P05177 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
HTR1A P08908 1/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16316796 0.92 ALDH1A1 (0.55) POLBALDH1A1MAPTPKMNR4A1
SCHEMBL394315 0.87 ALDH1A1 (0.53) POLBALDH1A1MAPTPKMKMT2A
SCHEMBL11800795 0.84 PKM (0.58) POLBALDH1A1PKMNR4A1RAB9A
SCHEMBL9568485 0.84 ALDH1A1 (0.50) ALDH1A1KMT2ALMNAGAACA1
SCHEMBL9614881 0.82 POLB (0.84) POLBALDH1A1RAB9AKMT2AMEN1
SCHEMBL17049845 0.81 KMT2A (0.65) ALDH1A1PKMKMT2AMEN1TSHR
SCHEMBL17633855 0.81 ALDH1A1 (0.50) POLBALDH1A1MAPTPKMKMT2A
SCHEMBL10153739 0.80 PKM (0.63) POLBALDH1A1MAPTPKMNR4A1
SCHEMBL28230856 0.80 ALDH1A1 (0.52) ALDH1A1TSHRLMNACA1CA2
SCHEMBL392740 0.79 ALDH1A1 (0.51) ALDH1A1MAPTKMT2AMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524116-B2 Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-8524116-B2 Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer FUJIFILM CORPORATION (JP) 2013-09-03 US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 US disclosed
US-20090040435-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-02-12 US disclosed
US-20080199637-A1 Optical Compensatory Film, Process for Producing the Same, and Polarizing Plate and Liquid Crystal Display Employing the Same FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7311949-B2 Composition, optical film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7311949-B2 Composition, optical film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 US disclosed
US-20070202275-A1 Coating composition for producing heat-sensitive transfer image-receiving sheet and heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed
US-20070002232-A1 Optical compensation film, polarizing plate and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 US disclosed